Cargando…
Synergistic Regulation of Transcription and Translation in Escherichia coli Revealed by Codirectional Increases in mRNA Concentration and Translation Efficiency
Translational regulation was investigated at the genome-scale in Escherichia coli cells. Using the polysome profiling method, the ribosome occupancy (RO) and ribosome density (RD) of different mRNA copies were determined for several hundred mRNAs during the exponential- and stationary-phases, provid...
Autores principales: | Nguyen, Huong Le, Duviau, Marie-Pierre, Laguerre, Sandrine, Nouaille, Sébastien, Cocaign-Bousquet, Muriel, Girbal, Laurence |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826937/ https://www.ncbi.nlm.nih.gov/pubmed/35138139 http://dx.doi.org/10.1128/spectrum.02041-21 |
Ejemplares similares
-
Multiplexing polysome profiling experiments to study translation in Escherichia coli
por: Nguyen, Huong Le, et al.
Publicado: (2019) -
When translation elongation is impaired, the mRNA is uniformly destabilized by the RNA degradosome, while the concentration of mRNA is altered along the molecule
por: Duviau, Marie-Pierre, et al.
Publicado: (2023) -
5’UTR sequences influence protein levels in Escherichia coli by regulating translation initiation and mRNA stability
por: Chen, Fan, et al.
Publicado: (2022) -
PNPase is involved in the coordination of mRNA degradation and expression in stationary phase cells of Escherichia coli
por: Dressaire, Clémentine, et al.
Publicado: (2018) -
The stability of an mRNA is influenced by its concentration: a potential physical mechanism to regulate gene expression
por: Nouaille, Sébastien, et al.
Publicado: (2017)