Synergistic Regulation of Transcription and Translation in Escherichia coli Revealed by Codirectional Increases in mRNA Concentration and Translation Efficiency

Translational regulation was investigated at the genome-scale in Escherichia coli cells. Using the polysome profiling method, the ribosome occupancy (RO) and ribosome density (RD) of different mRNA copies were determined for several hundred mRNAs during the exponential- and stationary-phases, provid...

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Detalles Bibliográficos
Autores principales: Nguyen, Huong Le, Duviau, Marie-Pierre, Laguerre, Sandrine, Nouaille, Sébastien, Cocaign-Bousquet, Muriel, Girbal, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826937/
https://www.ncbi.nlm.nih.gov/pubmed/35138139
http://dx.doi.org/10.1128/spectrum.02041-21