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Cu(ii)-based DNA labeling identifies the structural link between transcriptional activation and termination in a metalloregulator

Understanding the structural and mechanistic details of protein-DNA interactions that lead to cellular defence against toxic metal ions in pathogenic bacteria can lead to new ways of combating their virulence. Herein, we examine the Copper Efflux Regulator (CueR) protein, a transcription factor whic...

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Detalles Bibliográficos
Autores principales: Casto, Joshua, Mandato, Alysia, Hofmann, Lukas, Yakobov, Idan, Ghosh, Shreya, Ruthstein, Sharon, Saxena, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827015/
https://www.ncbi.nlm.nih.gov/pubmed/35282619
http://dx.doi.org/10.1039/d1sc06563g