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ECM1 modified HF-MSCs targeting HSC attenuate liver cirrhosis by inhibiting the TGF-β/Smad signaling pathway

Hair follicle-derived mesenchymal stem cells (HF-MSCs) show considerable therapeutic potential for liver cirrhosis (LC). To improve the effectiveness of naïve HF-MSC treatments on LC, we used bioinformatic tools to identify an exogenous gene targeting HSCs among the differentially expressed genes (D...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Lv, Chengqian, Huang, Qianqian, Zhao, Lei, Sun, Xiaoli, Ning, Dandan, Liu, Jingyang, Jiang, Yanan, Jin, Shizhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827057/
https://www.ncbi.nlm.nih.gov/pubmed/35136027
http://dx.doi.org/10.1038/s41420-022-00846-4