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Exosome-mediated miR-7-5p delivery enhances the anticancer effect of Everolimus via blocking MNK/eIF4E axis in non-small cell lung cancer

Everolimus is a kind of mammalian target of rapamycin (mTOR) inhibitors. Activated mitogen-activated protein kinase interacting kinases/eukaryotic translation initiation factor 4E (MNK/eIF4E) axis plays a crucial role in resistance to Everolimus in non-small cell lung cancer (NSCLC). The eIF4E phosp...

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Detalles Bibliográficos
Autores principales: Liu, Sile, Wang, Weiyuan, Ning, Yue, Zheng, Hongmei, Zhan, Yuting, Wang, Haihua, Yang, Yang, Luo, Jiadi, Wen, Qiuyuan, Zang, Hongjing, Peng, Jinwu, Ma, Jian, Fan, Songqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827062/
https://www.ncbi.nlm.nih.gov/pubmed/35136028
http://dx.doi.org/10.1038/s41419-022-04565-7