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Modeling axonal regeneration by changing cytoskeletal dynamics in stem cell-derived motor nerve organoids

Oxidative stress triggers axon degeneration and cell death, leading to the development of neurodegenerative diseases. Spinal motor nerves project very long axons, increasing the burden on axonal transport and metabolism. As such, spinal motor nerves are expected to be susceptible to oxidative stress...

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Detalles Bibliográficos
Autores principales: Seo, Woo Min, Yoon, Jiyoung, Lee, Ju-Hyun, Lee, Yunjeong, Lee, Hojae, Geum, Dongho, Sun, Woong, Song, Mi-Ryoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827082/
https://www.ncbi.nlm.nih.gov/pubmed/35136073
http://dx.doi.org/10.1038/s41598-022-05645-6