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Modeling axonal regeneration by changing cytoskeletal dynamics in stem cell-derived motor nerve organoids
Oxidative stress triggers axon degeneration and cell death, leading to the development of neurodegenerative diseases. Spinal motor nerves project very long axons, increasing the burden on axonal transport and metabolism. As such, spinal motor nerves are expected to be susceptible to oxidative stress...
Autores principales: | Seo, Woo Min, Yoon, Jiyoung, Lee, Ju-Hyun, Lee, Yunjeong, Lee, Hojae, Geum, Dongho, Sun, Woong, Song, Mi-Ryoung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827082/ https://www.ncbi.nlm.nih.gov/pubmed/35136073 http://dx.doi.org/10.1038/s41598-022-05645-6 |
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