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Clemastine Enhances Myelination, Delays Axonal Loss and Promotes Functional Recovery in Spinal Cord Injury

Recent evidence has shown that demyelination occurs along with axonal degeneration in spinal cord injury (SCI) during the secondary injury phase. Oligodendrocyte precursor cells (OPC) are present in the lesions but fail to differentiate into mature oligodendrocytes and form new myelin. Given the lim...

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Detalles Bibliográficos
Autores principales: Du, Weihong, Deng, Yongbing, Jiang, Rong, Tong, Luyao, Li, Ruixue, Jiang, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827101/
https://www.ncbi.nlm.nih.gov/pubmed/34661796
http://dx.doi.org/10.1007/s11064-021-03465-0