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Clemastine Enhances Myelination, Delays Axonal Loss and Promotes Functional Recovery in Spinal Cord Injury
Recent evidence has shown that demyelination occurs along with axonal degeneration in spinal cord injury (SCI) during the secondary injury phase. Oligodendrocyte precursor cells (OPC) are present in the lesions but fail to differentiate into mature oligodendrocytes and form new myelin. Given the lim...
Autores principales: | Du, Weihong, Deng, Yongbing, Jiang, Rong, Tong, Luyao, Li, Ruixue, Jiang, Xue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827101/ https://www.ncbi.nlm.nih.gov/pubmed/34661796 http://dx.doi.org/10.1007/s11064-021-03465-0 |
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