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The effects of extracellular vesicles derived from Krüppel-Like Factor 2 overexpressing endothelial cells on the regulation of cardiac inflammation in the dilated cardiomyopathy

BACKGROUND: Dilated cardiomyopathy (DCM) is one of the common causes of heart failure. Myocardial injury triggers an inflammatory response and recruits immune cells into the heart. High expression of Krüppel-like factor 2 (KLF2) in endothelial cells (ECs) potentially exerts an anti-inflammatory effe...

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Detalles Bibliográficos
Autores principales: Zhang, Wenfeng, Chen, Ziwei, Qiao, Shuaihua, Chen, Siyuan, Zheng, Hongyan, Wei, Xuan, Li, Qiaoling, Xu, Biao, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827179/
https://www.ncbi.nlm.nih.gov/pubmed/35139878
http://dx.doi.org/10.1186/s12951-022-01284-1