Loss of Drosophila Coq8 results in impaired survival, locomotor deficits and photoreceptor degeneration

Coenzyme Q8A encodes the homologue of yeast coq8, an ATPase that is required for the biosynthesis of Coenzyme Q10, an essential component of the electron transport chain. Mutations in COQ8A in humans result in CoQ10 deficiency, the clinical features of which include early-onset cerebellar ataxia, se...

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Detalles Bibliográficos
Autores principales: Hura, Angelia J., Hawley, Hannah R., Tan, Wei Jun, Penny, Rebecca J., Jacobsen, Jessie C., Fitzsimons, Helen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Micro Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827264/
https://www.ncbi.nlm.nih.gov/pubmed/35139868
http://dx.doi.org/10.1186/s13041-022-00900-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827264/
https://www.ncbi.nlm.nih.gov/pubmed/35139868
http://dx.doi.org/10.1186/s13041-022-00900-3

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