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Loss of Drosophila Coq8 results in impaired survival, locomotor deficits and photoreceptor degeneration
Coenzyme Q8A encodes the homologue of yeast coq8, an ATPase that is required for the biosynthesis of Coenzyme Q10, an essential component of the electron transport chain. Mutations in COQ8A in humans result in CoQ10 deficiency, the clinical features of which include early-onset cerebellar ataxia, se...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827264/ https://www.ncbi.nlm.nih.gov/pubmed/35139868 http://dx.doi.org/10.1186/s13041-022-00900-3 |