Up-regulation of MTHFD2 is associated with clinicopathological characteristics and poor survival in ovarian cancer, possibly by regulating MOB1A signaling

BACKGROUND: MTHFD2 is a folate-coupled metabolic enzyme, which has been proved to participant in the metabolic reprogramming and tumor cell-sustaining proliferative capacity. However, the function of MTHFD2 in the development of ovarian cancer and its potential molecular mechanisms is still unclear....

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Detalles Bibliográficos
Autores principales: Cui, Xiangrong, Su, Huancheng, Yang, Jiaolin, Wu, Xueqing, Huo, Kai, Jing, Xuan, Zhang, Sanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827288/
https://www.ncbi.nlm.nih.gov/pubmed/35135596
http://dx.doi.org/10.1186/s13048-022-00954-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827288/
https://www.ncbi.nlm.nih.gov/pubmed/35135596
http://dx.doi.org/10.1186/s13048-022-00954-w

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