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Evidence for Shared Genetic Aetiology Between Schizophrenia, Cardiometabolic, and Inflammation-Related Traits: Genetic Correlation and Colocalization Analyses

BACKGROUND: Schizophrenia commonly co-occurs with cardiometabolic and inflammation-related traits. It is unclear to what extent the comorbidity could be explained by shared genetic aetiology. METHODS: We used GWAS data to estimate shared genetic aetiology between schizophrenia, cardiometabolic, and...

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Detalles Bibliográficos
Autores principales: Perry, Benjamin I, Bowker, Nicholas, Burgess, Stephen, Wareham, Nicholas J, Upthegrove, Rachel, Jones, Peter B, Langenberg, Claudia, Khandaker, Golam M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827407/
https://www.ncbi.nlm.nih.gov/pubmed/35156041
http://dx.doi.org/10.1093/schizbullopen/sgac001