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Evolution of cefiderocol resistance in Stenotrophomonas maltophilia using in vitro serial passage techniques

OBJECTIVES: Cefiderocol is a siderophore cephalosporin active against MDR Gram-negatives including Stenotrophomonas maltophilia. Cefiderocol resistance remains uncommon and incompletely understood. We selected for cefiderocol-resistant S. maltophilia in vitro and characterized the genetic mechanisms...

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Detalles Bibliográficos
Autores principales: Werth, Brian J., Ashford, Nathaniel K., Penewit, Kelsi, Waalkes, Adam, Holmes, Elizabeth A., Bryan, Andrew, Salipante, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827560/
https://www.ncbi.nlm.nih.gov/pubmed/35156034
http://dx.doi.org/10.1093/jacamr/dlac011