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DExD/H-box helicase 9 intrinsically controls CD8(+) T cell–mediated antiviral response through noncanonical mechanisms

Upon virus infection, CD8(+) T cell accumulation is tightly controlled by simultaneous proliferation and apoptosis. However, it remains unclear how TCR signal coordinates these events to achieve expansion and effector cell differentiation. We found that T cell–specific deletion of nuclear helicase D...

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Detalles Bibliográficos
Autores principales: Jiao, Anjun, Sun, Chenming, Wang, Xin, Lei, Lei, Liu, Haiyan, Li, Wenhui, Yang, Xiaofeng, Zheng, Huiqiang, Ding, Renyi, Zhu, Kun, Su, Yanhong, Zhang, Cangang, Zhang, Lianjun, Zhang, Baojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827654/
https://www.ncbi.nlm.nih.gov/pubmed/35138904
http://dx.doi.org/10.1126/sciadv.abk2691