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27558 Obeticholic acid (OCALIVA ®) protects against 2,8-dihydroxyadenine nephropathy in mice

ABSTRACT IMPACT: This work may lead to new treatments for crystalline nephropathies. OBJECTIVES/GOALS: This study investigated obeticholic acid (OCALIVA ®) as a potential treatment for 2,8-dihydroxyadenine (2,8-DHA) nephropathy using a mouse model. The treatment was investigated in both sexes at two...

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Detalles Bibliográficos
Autores principales: Jones, Bryce, Benitez, Carlos, Cruz, Idalia, Myakala, Komuraiah, Wang, Xiaoxin, Libby, Andrew, Rowland, Emma, Kurtz, Ryan, Rosenberg, Avi, Levi, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827674/
http://dx.doi.org/10.1017/cts.2021.428