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68722 Role of ER calcium in beta cell senescence and diabetes pathophysiology

ABSTRACT IMPACT: The proposed study has the potential to inform new paradigms of type 1 diabetes prevention and therapy with the overall goal of improving β cell health during autoimmunity. OBJECTIVES/GOALS: Type 1 diabetes (T1D) results from immune-mediated destruction of pancreatic βcells. Recent...

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Detalles Bibliográficos
Autores principales: Weaver, Staci A., Kono, Tatsuyoshi, Syed, Farooq, Bone, Robert, Evans-Molina, Carmella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827744/
http://dx.doi.org/10.1017/cts.2021.446