52350 PKM2 mediates anti-tumor immunity and T cell dysfunction

ABSTRACT IMPACT: T cell dysfunction is a dominant suppressor of anti-tumor immunity, reducing immunotherapeutic efficacy and benefit to patients; our work will identify novel mediators of this process for both therapeutic potential and underlying mechanism, allowing for both potential immediate clin...

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Detalles Bibliográficos
Autores principales: Markowitz, Geoffrey, Ban, Yi, Crowley, Michael, Tavarez, Diamile, Wong, Stephen T.C., Chang, Kenneth, Schietinger, Andrea, Altorki, Nasser, Mittal, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Mechanistic Basic to Clinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827797/
http://dx.doi.org/10.1017/cts.2021.630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827797/
http://dx.doi.org/10.1017/cts.2021.630

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