Cargando…

38766 Massively Parallel Reporter Assay Reveals Functional Impact of 3™-UTR SNPs Associated with Neurological and Psychiatric Disorders

ABSTRACT IMPACT: Screening the effect of thousands of non-coding genetic variants will help identify variants important in the etiology of diseases OBJECTIVES/GOALS: Massively parallel reporter assays (MPRAs) can experimentally evaluate the impact of genetic variants on gene expression. In this stud...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Andy B., Thapa, Kriti, Gao, Hongyu, Reiter, Jill L., Zhang, Junjie, Xuei, Xiaoling, Gu, Hongmei, Wang, Yue, Edenberg, Howard J., Liu, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827855/
http://dx.doi.org/10.1017/cts.2021.645