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38766 Massively Parallel Reporter Assay Reveals Functional Impact of 3™-UTR SNPs Associated with Neurological and Psychiatric Disorders

ABSTRACT IMPACT: Screening the effect of thousands of non-coding genetic variants will help identify variants important in the etiology of diseases OBJECTIVES/GOALS: Massively parallel reporter assays (MPRAs) can experimentally evaluate the impact of genetic variants on gene expression. In this stud...

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Detalles Bibliográficos
Autores principales:	Chen, Andy B., Thapa, Kriti, Gao, Hongyu, Reiter, Jill L., Zhang, Junjie, Xuei, Xiaoling, Gu, Hongmei, Wang, Yue, Edenberg, Howard J., Liu, Yunlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2021
Materias:	Mechanistic Basic to Clinical
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827855/ http://dx.doi.org/10.1017/cts.2021.645

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