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89723 CD105-targeted CAR T cells for the treatment of acute myeloid leukemia

ABSTRACT IMPACT: Our work might lead to a new treatment for patients with acute myeloid leukemia OBJECTIVES/GOALS: Acute myeloid leukemia (AML) is a devastating hematologic malignancy, with dismal 5-year survival. Chimeric antigen receptor (CAR) T cells have been approved for B cell malignancies but...

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Detalles Bibliográficos
Autores principales: Lontos, Konstantinos, Wang, Yiyang, Frisch, Andrew, Colbert, Mason, Lohmueller, Jason, Delgoffe, Greg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827872/
http://dx.doi.org/10.1017/cts.2021.450