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88462 Fluconazole distribution in CNS and gynecological tissues in HIV-related cryptococcal meningitis decedents

ABSTRACT IMPACT: Plasma and CSF are not reliable estimates of drug exposure in tissue compartments relevant for treatment and prevention of infectious diseases. OBJECTIVES/GOALS: Globally, high dose fluconazole is widely used in the management of cryptococcal meningitis. While it is known to readily...

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Detalles Bibliográficos
Autores principales: Nicol, Melanie R., Wang, Fan, Richard, Ambayo, Namuju, Olivie Carolyne, Pastick, Katelyn A, Boulware, David R, Meya, David B, Lukande, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827950/
http://dx.doi.org/10.1017/cts.2021.648