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38081 A Whole Blood Signature of Neutrophil Expression and Adaptive Immune Downregulation Characterizes Sepsis Mortality

ABSTRACT IMPACT: This work identifies host immune perturbations in sepsis mortality that suggests targets for a precision medicine paradigm in the host response to infection. OBJECTIVES/GOALS: To compare the early whole blood transcriptome during sepsis between 30-day survivors and non-survivors in...

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Detalles Bibliográficos
Autores principales: Giannini, H.M., Cosgriff, C.V., Lu, X.M., Reilly, J.R., Anderson, B.J., Jones, T.K., Ittner, C.A.G., Weissman, A.R., Agyeum, T., Dunn, T., Shashaty, M., Meyer, N.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827958/
http://dx.doi.org/10.1017/cts.2021.662