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95332 Intestinal inflammation and altered gut microbiota associated with inflammatory bowel disease render mice susceptible to Clostridioides difficile colonization and infection

ABSTRACT IMPACT: Use of this novel murine model of inflammatory bowel disease (IBD) and C. difficile infection (CDI) will aid in developing new clinical approaches to predict, diagnose, and treat CDI in the IBD population. OBJECTIVES/GOALS: IBD is associated with intestinal inflammation and alterati...

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Detalles Bibliográficos
Autores principales: Barron, Lisa Abernathy-Closedeline R., George, James M., Vendrov, Kimberly C., Higgins, Peter D.R., Bergin, Ingrid L., Young, Vincent B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8827995/
http://dx.doi.org/10.1017/cts.2021.634