55484 Dual activation of CAR and Nrf2 improves the efficacy: toxicity ratio of cyclophosphamide and doxorubicin-based treatment of TNBC

ABSTRACT IMPACT: Triple negative breast cancer (TNBC) affects 10-20% of women with breast cancer and is biologically more aggressive than other subtypes. The novel compound we have developed, DL7076, would give clinicians a vital strategy to improve the commonly used cyclophosphamide (CPA) and doxor...

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Detalles Bibliográficos
Autores principales: Stern, Sydney, Liang, Dongdong, Li, Linhao, Kurian, Ritika, Lynch, Caitlin, Heyward, Scott, Kareem, Ajoke, Chun, Young, Hong, Charles, Xue, Fengtian, Wang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Mechanistic Basic to Clinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828015/
http://dx.doi.org/10.1017/cts.2021.653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828015/
http://dx.doi.org/10.1017/cts.2021.653

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