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Recapitulation of dyssynchrony-associated contractile impairment in asymmetrically paced engineered heart tissue

BACKGROUND: One third of heart failure patients exhibit dyssynchronized electromechanical activity of the heart (evidenced by a broad QRS-complex). Cardiac resynchronization therapy (CRT) in the form of biventricular pacing improves cardiac output and clinical outcome of responding patients. Technic...

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Detalles Bibliográficos
Autores principales: Stenzig, Justus, Lemoine, Marc D., Stoter, Aaltje M.S., Wrona, Kinga M., Lemme, Marta, Mulla, Wesam, Etzion, Yoram, Eschenhagen, Thomas, Hirt, Marc N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828044/
https://www.ncbi.nlm.nih.gov/pubmed/34634355
http://dx.doi.org/10.1016/j.yjmcc.2021.10.001