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Alkbh1‐mediated DNA N6‐methyladenine modification regulates bone marrow mesenchymal stem cell fate during skeletal aging

OBJECTIVES: DNA N6‐methyladenine (N6‐mA) demethylase Alkbh1 participates in regulating osteogenic differentiation of mesenchymal stem cell (MSCs) and vascular calcification. However, the role of Alkbh1 in bone metabolism remains unclear. MATERIALS AND METHODS: Bone marrow mesenchymal stem cells (BMS...

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Detalles Bibliográficos
Autores principales: Cai, Guang‐Ping, Liu, Ya‐Lin, Luo, Li‐Ping, Xiao, Ye, Jiang, Tie‐Jian, Yuan, Jian, Wang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828262/
https://www.ncbi.nlm.nih.gov/pubmed/35018683
http://dx.doi.org/10.1111/cpr.13178