Investigating novel thiazolyl-indazole derivatives as scaffolds for SARS-CoV-2 M(Pro) inhibitors

COVID-19 is a global pandemic caused by infection with the SARS-CoV-2 virus. Remdesivir, a SARS-CoV-2 RNA polymerase inhibitor, is the only drug to have received widespread approval for treatment of COVID-19. The SARS-CoV-2 main protease enzyme (M(Pro)), essential for viral replication and transcrip...

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Detalles Bibliográficos
Autores principales: Airas, Justin, Bayas, Catherine A., N'Ait Ousidi, Abdellah, Ait Itto, Moulay Youssef, Auhmani, Aziz, Loubidi, Mohamed, Esseffar, M'hamed, Pollock, Julie A., Parish, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Masson SAS. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828376/
https://www.ncbi.nlm.nih.gov/pubmed/37519829
http://dx.doi.org/10.1016/j.ejmcr.2022.100034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828376/
https://www.ncbi.nlm.nih.gov/pubmed/37519829
http://dx.doi.org/10.1016/j.ejmcr.2022.100034

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