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Integrin mediates cell entry of the SARS-CoV-2 virus independent of cellular receptor ACE2

Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is broadly accepted that SARS-CoV-2 utilizes its spike protein to recognize the extracellular domain of angiotensin-converting enzyme 2 (ACE2) to enter cells...

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Detalles Bibliográficos
Autores principales: Liu, Jiamnin, Lu, Fan, Chen, Yinghua, Plow, Edward, Qin, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828381/
https://www.ncbi.nlm.nih.gov/pubmed/35150743
http://dx.doi.org/10.1016/j.jbc.2022.101710