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Identifying temporal and spatial patterns of variation from multimodal data using MEFISTO

Factor analysis is a widely used method for dimensionality reduction in genome biology, with applications from personalized health to single-cell biology. Existing factor analysis models assume independence of the observed samples, an assumption that fails in spatio-temporal profiling studies. Here...

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Detalles Bibliográficos
Autores principales: Velten, Britta, Braunger, Jana M., Argelaguet, Ricard, Arnol, Damien, Wirbel, Jakob, Bredikhin, Danila, Zeller, Georg, Stegle, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828471/
https://www.ncbi.nlm.nih.gov/pubmed/35027765
http://dx.doi.org/10.1038/s41592-021-01343-9