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Targeting Thyrointegrin αvβ3 Using Fluorobenzyl Polyethylene Glycol Conjugated Tetraiodothyroacetic Acid (NP751) in Acute Myeloid Leukemia

BACKGROUND: Acute myeloid leukemia (AML) is associated with poor long-term survival, even with newer therapeutic agents. Here, we show the results of our preclinical study, in which we evaluated the efficacy of a new thyrointegrin αvβ3 antagonist, named fluorobenzyl polyethylene glycol conjugated te...

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Detalles Bibliográficos
Autores principales: Darwish, Noureldien H. E., Glinsky, Gennadi V., Sudha, Thangirala, Mousa, Shaker A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828484/
https://www.ncbi.nlm.nih.gov/pubmed/35155195
http://dx.doi.org/10.3389/fonc.2021.793810