Synthesis of N-Heteroarenemethyl Esters via C–C Bond Cleavage of Acyl Cyanides Under Transition Metal-Free Conditions

A practical method to synthesize N-heteroaryl esters from N-heteroaryl methanols with acyl cyanides via C–C bond cleavage without using any transition metal is demonstrated here. The use of Na(2)CO(3)/15-crown-5 couple enables access to a series of N-heteroaryl esters in high efficiency. This protoc...

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Detalles Bibliográficos
Autores principales: Lai, Miao, Su, Fangyao, Hu, Jingyi, Wang, Mengzhuo, Zhao, Mingqin, Zhang, Ganlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828493/
https://www.ncbi.nlm.nih.gov/pubmed/35155384
http://dx.doi.org/10.3389/fchem.2021.822625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828493/
https://www.ncbi.nlm.nih.gov/pubmed/35155384
http://dx.doi.org/10.3389/fchem.2021.822625

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