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Synthesis of N-Heteroarenemethyl Esters via C–C Bond Cleavage of Acyl Cyanides Under Transition Metal-Free Conditions
A practical method to synthesize N-heteroaryl esters from N-heteroaryl methanols with acyl cyanides via C–C bond cleavage without using any transition metal is demonstrated here. The use of Na(2)CO(3)/15-crown-5 couple enables access to a series of N-heteroaryl esters in high efficiency. This protoc...
Autores principales: | Lai, Miao, Su, Fangyao, Hu, Jingyi, Wang, Mengzhuo, Zhao, Mingqin, Zhang, Ganlin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828493/ https://www.ncbi.nlm.nih.gov/pubmed/35155384 http://dx.doi.org/10.3389/fchem.2021.822625 |
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