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YAP1 regulates the self-organized fate patterning of hESC-derived gastruloids

The gastrulation process relies on complex interactions between developmental signaling pathways that are not completely understood. Here, we interrogated the contribution of the Hippo signaling effector YAP1 to the formation of the three germ layers by analyzing human embryonic stem cell (hESC)-der...

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Detalles Bibliográficos
Autores principales: Stronati, Eleonora, Giraldez, Servando, Huang, Ling, Abraham, Elizabeth, McGuire, Gillian R., Hsu, Hui-Ting, Jones, Kathy A., Estarás, Conchi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828531/
https://www.ncbi.nlm.nih.gov/pubmed/35063126
http://dx.doi.org/10.1016/j.stemcr.2021.12.012