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YAP1 regulates the self-organized fate patterning of hESC-derived gastruloids
The gastrulation process relies on complex interactions between developmental signaling pathways that are not completely understood. Here, we interrogated the contribution of the Hippo signaling effector YAP1 to the formation of the three germ layers by analyzing human embryonic stem cell (hESC)-der...
Autores principales: | Stronati, Eleonora, Giraldez, Servando, Huang, Ling, Abraham, Elizabeth, McGuire, Gillian R., Hsu, Hui-Ting, Jones, Kathy A., Estarás, Conchi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828531/ https://www.ncbi.nlm.nih.gov/pubmed/35063126 http://dx.doi.org/10.1016/j.stemcr.2021.12.012 |
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