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Reconstruction of dynamic regulatory networks reveals signaling-induced topology changes associated with germ layer specification

Elucidating regulatory relationships between transcription factors (TFs) and target genes is fundamental to understanding how cells control their identity and behavior. Unfortunately, existing computational gene regulatory network (GRN) reconstruction methods are imprecise, computationally burdensom...

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Detalles Bibliográficos
Autores principales: Su, Emily Y., Spangler, Abby, Bian, Qin, Kasamoto, Jessica Y., Cahan, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828556/
https://www.ncbi.nlm.nih.gov/pubmed/35090587
http://dx.doi.org/10.1016/j.stemcr.2021.12.018