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Reconstruction of dynamic regulatory networks reveals signaling-induced topology changes associated with germ layer specification
Elucidating regulatory relationships between transcription factors (TFs) and target genes is fundamental to understanding how cells control their identity and behavior. Unfortunately, existing computational gene regulatory network (GRN) reconstruction methods are imprecise, computationally burdensom...
Autores principales: | Su, Emily Y., Spangler, Abby, Bian, Qin, Kasamoto, Jessica Y., Cahan, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828556/ https://www.ncbi.nlm.nih.gov/pubmed/35090587 http://dx.doi.org/10.1016/j.stemcr.2021.12.018 |
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