rasH2 mouse: reproducibility and stability of carcinogenicity due to a standardized production and monitoring system

The rasH2 mouse was developed as a model for carcinogenicity studies in regulatory science. Its phenotype is stable during high-volume production and over successive generations. To produce rasH2 mice, three strains of mice (C57BL/6J-TgrasH2, C57BL/6J, and BALB/cByJ) were maintained individually. Si...

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Detalles Bibliográficos
Autores principales: Tsutsumi, Hideki, Inoue, Ryo, Yasuda, Masahiko, Takahashi, Riichi, Suzuki, Masami, Urano, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2021
Materias:
Concise Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828604/
https://www.ncbi.nlm.nih.gov/pubmed/35221492
http://dx.doi.org/10.1293/tox.2021-0068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828604/
https://www.ncbi.nlm.nih.gov/pubmed/35221492
http://dx.doi.org/10.1293/tox.2021-0068

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