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Generation of a uniform thymic malignant lymphoma model with C57BL/6J p53 gene deficient mice

Lymphoma is the third most common cancer diagnosed in children, and T-cell lymphoma has the worst prognosis based on clinical observations. To date, a lymphoma model with uniform penetrance has not yet been developed. In this study, we generated a p53 deficient mouse model by targeting embryonic ste...

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Detalles Bibliográficos
Autores principales: Liu, Susu, Lyu, Jianjun, Li, Qianqian, Wu, Xi, Yang, Yanwei, Huo, Guitao, Zhu, Qingfen, Guo, Ming, Shen, Yuelei, Wang, Sanlong, Fan, Changfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828615/
https://www.ncbi.nlm.nih.gov/pubmed/35221493
http://dx.doi.org/10.1293/tox.2021-0022