Decreased Expression of Programmed Death Ligand-L1 by Seven in Absentia Homolog 2 in Cholangiocarcinoma Enhances T-Cell–Mediated Antitumor Activity

N6-methyladenosine (m6A) has been reported as an important mechanism of post-transcriptional regulation. Programmed death ligand 1 (PD-L1) is a primary immune inhibitory molecule expressed on tumor cells that promotes immune evasion. In addition, seven in absentia homolog 2 (Siah2), a RING E3 ubiqui...

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Detalles Bibliográficos
Autores principales: Zheng, Hao, Zheng, Wen-juan, Wang, Zhen-guang, Tao, Yuan-ping, Huang, Zhi-ping, Yang, Le, Ouyang, Liu, Duan, Zhi-qing, Zhang, Yi-nuo, Chen, Bo-ning, Xiang, Dai-min, Jin, Gang, Fang, Lu, Zhou, Fan, Liang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828655/
https://www.ncbi.nlm.nih.gov/pubmed/35154166
http://dx.doi.org/10.3389/fimmu.2022.845193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828655/
https://www.ncbi.nlm.nih.gov/pubmed/35154166
http://dx.doi.org/10.3389/fimmu.2022.845193

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