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Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune response

Legionella pneumophila is an intracellular bacterial pathogen that can cause a severe form of pneumonia in humans, a phenotype evolved through interactions with aquatic protozoa in the environment. Here, we show that L. pneumophila uses extracellular vesicles to translocate bacterial small RNAs (sRN...

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Detalles Bibliográficos
Autores principales: Sahr, Tobias, Escoll, Pedro, Rusniok, Christophe, Bui, Sheryl, Pehau-Arnaudet, Gérard, Lavieu, Gregory, Buchrieser, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828724/
https://www.ncbi.nlm.nih.gov/pubmed/35140216
http://dx.doi.org/10.1038/s41467-022-28454-x