Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling

DNA methylation microarrays can be employed to interrogate cell-type composition in complex tissues. Here, we expand reference-based deconvolution of blood DNA methylation to include 12 leukocyte subtypes (neutrophils, eosinophils, basophils, monocytes, naïve and memory B cells, naïve and memory CD4...

Descripción completa

Detalles Bibliográficos
Autores principales: Salas, Lucas A., Zhang, Ze, Koestler, Devin C., Butler, Rondi A., Hansen, Helen M., Molinaro, Annette M., Wiencke, John K., Kelsey, Karl T., Christensen, Brock C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828780/
https://www.ncbi.nlm.nih.gov/pubmed/35140201
http://dx.doi.org/10.1038/s41467-021-27864-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828780/
https://www.ncbi.nlm.nih.gov/pubmed/35140201
http://dx.doi.org/10.1038/s41467-021-27864-7

Ejemplares similares