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An optogenetic approach for regulating human parathyroid hormone secretion

Parathyroid hormone (PTH) plays crucial role in maintaining calcium and phosphorus homeostasis. In the progression of secondary hyperparathyroidism (SHPT), expression of calcium-sensing receptors (CaSR) in the parathyroid gland decreases, which leads to persistent hypersecretion of PTH. How to preci...

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Detalles Bibliográficos
Autores principales: Liu, Yunhui, Zhang, Lu, Hu, Nan, Shao, Jie, Yang, Dazhi, Ruan, Changshun, Huang, Shishu, Wang, Liping, Lu, William W., Zhang, Xinzhou, Yang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828854/
https://www.ncbi.nlm.nih.gov/pubmed/35140213
http://dx.doi.org/10.1038/s41467-022-28472-9