Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis

Aging and mechanical overload are prominent risk factors for osteoarthritis (OA), which lead to an imbalance in redox homeostasis. The resulting state of oxidative stress drives the pathological transition of chondrocytes during OA development. However, the specific molecular pathways involved in di...

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Detalles Bibliográficos
Autores principales: Kang, Donghyun, Lee, Jeeyeon, Jung, Jisu, Carlson, Bradley A., Chang, Moon Jong, Chang, Chong Bum, Kang, Seung-Baik, Lee, Byung Cheon, Gladyshev, Vadim N., Hatfield, Dolph L., Lee, Byeong Jae, Kim, Jin-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828855/
https://www.ncbi.nlm.nih.gov/pubmed/35140209
http://dx.doi.org/10.1038/s41467-022-28385-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828855/
https://www.ncbi.nlm.nih.gov/pubmed/35140209
http://dx.doi.org/10.1038/s41467-022-28385-7

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