The collagen receptor, discoidin domain receptor 2, functions in Gli1-positive skeletal progenitors and chondrocytes to control bone development

Discoidin Domain Receptor 2 (DDR2) is a collagen-activated receptor kinase that, together with integrins, is required for cells to respond to the extracellular matrix. Ddr2 loss-of-function mutations in humans and mice cause severe defects in skeletal growth and development. However, the cellular fu...

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Detalles Bibliográficos
Autores principales: Mohamed, Fatma F., Ge, Chunxi, Cowling, Randy T., Lucas, Daniel, Hallett, Shawn A., Ono, Noriaki, Binrayes, Abdul-Aziz, Greenberg, Barry, Franceschi, Renny T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828874/
https://www.ncbi.nlm.nih.gov/pubmed/35140200
http://dx.doi.org/10.1038/s41413-021-00182-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828874/
https://www.ncbi.nlm.nih.gov/pubmed/35140200
http://dx.doi.org/10.1038/s41413-021-00182-w

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