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Dominant Antiviral CD8(+) T Cell Responses Empower Prophylactic Antibody-Eliciting Vaccines Against Cytomegalovirus

Human cytomegalovirus (HCMV) is an ubiquitous herpesvirus that can cause serious morbidity and mortality in immunocompromised or immune-immature individuals. A vaccine that induces immunity to CMV in these target populations is therefore highly needed. Previous attempts to generate efficacious CMV v...

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Detalles Bibliográficos
Autores principales: Pardieck, Iris N., van Duikeren, Suzanne, Veerkamp, Dominique M. B., Brasem, Dena J., Redeker, Anke, van Bergen, Jeroen, Han, Wanda, Ossendorp, Ferry, Zondag, Gerben, Arens, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828907/
https://www.ncbi.nlm.nih.gov/pubmed/35154089
http://dx.doi.org/10.3389/fimmu.2022.680559