Cargando…

Dominant Antiviral CD8(+) T Cell Responses Empower Prophylactic Antibody-Eliciting Vaccines Against Cytomegalovirus

Human cytomegalovirus (HCMV) is an ubiquitous herpesvirus that can cause serious morbidity and mortality in immunocompromised or immune-immature individuals. A vaccine that induces immunity to CMV in these target populations is therefore highly needed. Previous attempts to generate efficacious CMV v...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pardieck, Iris N., van Duikeren, Suzanne, Veerkamp, Dominique M. B., Brasem, Dena J., Redeker, Anke, van Bergen, Jeroen, Han, Wanda, Ossendorp, Ferry, Zondag, Gerben, Arens, Ramon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828907/ https://www.ncbi.nlm.nih.gov/pubmed/35154089 http://dx.doi.org/10.3389/fimmu.2022.680559

Ejemplares similares

A poly-neoantigen DNA vaccine synergizes with PD-1 blockade to induce T cell-mediated tumor control
por: Tondini, Elena, et al.
Publicado: (2019)

Cytomegalovirus infection and progressive differentiation of effector-memory T cells
por: Pardieck, Iris N., et al.
Publicado: (2018)

The Breadth of Synthetic Long Peptide Vaccine-Induced CD8(+) T Cell Responses Determines the Efficacy against Mouse Cytomegalovirus Infection
por: Panagioti, Eleni, et al.
Publicado: (2016)

A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection
por: Pardieck, Iris N., et al.
Publicado: (2022)

FcγRI expression on macrophages is required for antibody-mediated tumor protection by cytomegalovirus-based vaccines
por: Benonisson, Hreinn, et al.
Publicado: (2018)

The viral context instructs the redundancy of costimulatory pathways in driving CD8(+) T cell expansion
por: Welten, Suzanne PM, et al.
Publicado: (2015)

Predicting the efficacy of cancer vaccines by evaluating T-cell responses
por: van Duikeren, Suzanne, et al.
Publicado: (2013)

Enforced OX40 Stimulation Empowers Booster Vaccines to Induce Effective CD4(+) and CD8(+) T Cell Responses against Mouse Cytomegalovirus Infection
por: Panagioti, Eleni, et al.
Publicado: (2017)

Improving Adoptive T Cell Therapy: The Particular Role of T Cell Costimulation, Cytokines, and Post-Transfer Vaccination
por: Redeker, Anke, et al.
Publicado: (2016)

Enhanced Cross-Presentation and Improved CD8(+) T Cell Responses after Mannosylation of Synthetic Long Peptides in Mice
por: Rauen, Judith, et al.
Publicado: (2014)

Memory CD8(+) T cell heterogeneity is primarily driven by pathogen-specific cues and additionally shaped by the tissue environment
por: van der Gracht, Esmé T.I., et al.
Publicado: (2020)

PD-L1 blockade engages tumor-infiltrating lymphocytes to co-express targetable activating and inhibitory receptors
por: Beyrend, Guillaume, et al.
Publicado: (2019)

The Contribution of Cytomegalovirus Infection to Immune Senescence Is Set by the Infectious Dose
por: Redeker, Anke, et al.
Publicado: (2018)

Local immunomodulation for cancer therapy: Providing treatment where needed
por: Fransen, Marieke F, et al.
Publicado: (2013)

Cytofast: A workflow for visual and quantitative analysis of flow and mass cytometry data to discover immune signatures and correlations
por: Beyrend, Guillaume, et al.
Publicado: (2018)

Delayed vaccine-induced CD8(+) T cell expansion by topoisomerase I inhibition mediates enhanced CD70-dependent tumor eradication
por: van der Sluis, Tetje C, et al.
Publicado: (2023)

Identification of a neo-epitope dominating endogenous CD8 T cell responses to MC-38 colorectal cancer
por: Hos, Brett J., et al.
Publicado: (2019)

Synergy of therapeutic vaccination against HPV16 oncogenic proteins and standard chemotherapeutics
por: Melief, Cornelis J, et al.
Publicado: (2014)

Human cytomegalovirus elicits fetal γδ T cell responses in utero
por: Vermijlen, David, et al.
Publicado: (2010)

Combining Photodynamic Therapy with Immunostimulatory Nanoparticles Elicits Effective Anti-Tumor Immune Responses in Preclinical Murine Models
por: Huis in ‘t Veld, Ruben Victor, et al.
Publicado: (2021)

OX40 agonism enhances PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum
por: van der Sluis, Tetje C., et al.
Publicado: (2023)

Immune Checkpoint Therapy: Tumor Draining Lymph Nodes in the Spotlights
por: Fransen, Marieke F., et al.
Publicado: (2021)

Effectiveness of Prophylactic Human Cytomegalovirus Hyperimmunoglobulin in Preventing Cytomegalovirus Infection following Transplantation: A Systematic Review and Meta-Analysis
por: Barten, Markus J., et al.
Publicado: (2022)

Prophylactic Cancer Vaccines Engineered to Elicit Specific Adaptive Immune Response
por: Crews, Davis W., et al.
Publicado: (2021)

Advanced colorectal cancer resulting in acute bowel obstruction during pregnancy; a case report
por: Ossendorp, Rikkert R., et al.
Publicado: (2016)

Time to Empower Release of Insects Carrying a Dominant Lethal and Wolbachia Against Zika
por: Dickens, Borame L., et al.
Publicado: (2016)

Empowering grassroots innovation to accelerate biomedical research
por: Greshake Tzovaras, Bastian, et al.
Publicado: (2021)

The hallmarks of CMV-specific CD8 T-cell differentiation
por: van den Berg, Sara P. H., et al.
Publicado: (2019)

Cationic Nanoparticle-Based Cancer Vaccines
por: Heuts, Jeroen, et al.
Publicado: (2021)

“Unlicensed” Natural Killer cells dominate the response to cytomegalovirus infection
por: Orr, Mark T., et al.
Publicado: (2010)

Editorial: Immunity to Cytomegalovirus Infections: Challenges and Therapeutic Opportunities
por: Alonso-Arias, Rebeca, et al.
Publicado: (2022)

Cytomegalovirus infection exacerbates autoimmune mediated neuroinflammation
por: Vanheusden, Marjan, et al.
Publicado: (2017)

Soyon Hong: My role is to empower
por: Van Emmenis, Lucie
Publicado: (2023)

Approaches to Improve Chemically Defined Synthetic Peptide Vaccines
por: Hos, Brett J., et al.
Publicado: (2018)

PD-L1 immune suppression in cancer: Tumor cells or host cells?
por: Kleinovink, Jan Willem, et al.
Publicado: (2017)

EZH2-Myc driven glioblastoma elicited by cytomegalovirus infection of human astrocytes
por: El Baba, Ranim, et al.
Publicado: (2023)

Empowered leaders
por: Finzel, Hans, et al.
Publicado: (2002)

The Empowered Manager
por: Block, Peter
Publicado: (2016)

Empowering anesthesiologists
por: Kapoor, Mukul Chandra
Publicado: (2015)

Empowering mothers
por: Seshadri, Tanya, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_9eu4mgut1ui2q977ed87tffdg8