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Arylamine N-Acetyltransferase 1 Activity is Regulated by the Protein Acetylation Status

Arylamine N-acetyltransferase 1 (NAT1) is a drug metabolizing enzyme that influences cancer cell proliferation and survival, especially in breast cancer. Lysine-acetylation is an important Post-Translational Modification (PTM) in the regulation of diverse cellular processes. Histone deacetylases (HD...

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Detalles Bibliográficos
Autores principales: Salazar-González, Raúl A., Doll, Mark A., Hein, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828969/
https://www.ncbi.nlm.nih.gov/pubmed/35153780
http://dx.doi.org/10.3389/fphar.2022.797469