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Genetically increased circulating FUT3 level leads to reduced risk of idiopathic pulmonary fibrosis: a Mendelian randomisation study

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal fibrotic interstitial lung disease. Few circulating biomarkers have been identified to have causal effects on IPF. METHODS: To identify candidate IPF-influencing circulating proteins, we undertook an efficient screen of circulat...

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Detalles Bibliográficos
Autores principales: Nakanishi, Tomoko, Cerani, Agustin, Forgetta, Vincenzo, Zhou, Sirui, Allen, Richard J., Leavy, Olivia C., Koido, Masaru, Assayag, Deborah, Jenkins, R. Gisli, Wain, Louise V., Yang, Ivana V., Lathrop, G. Mark, Wolters, Paul J., Schwartz, David A., Richards, J. Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8828995/
https://www.ncbi.nlm.nih.gov/pubmed/34172473
http://dx.doi.org/10.1183/13993003.03979-2020